Jan 30, 2014

Letrozole by QD Labs - exceptional estrogen reducer

Letrozole is considered to be one of the most widely used estrogen reducers in today’s steroid market. This is because it can offer greater benefits than Nolvadex or Proviron when it comes to reducing or eliminating estrogen levels. This drug is also used by members of the medical fraternity for handling cases of infertility for ovulation induction. In addition to that, it is also hailed as an exceptional product when it comes to reversing the spread and extent of breast cancer after treatment options such as Tamoxifen therapy have failed to deliver any results.

Femara is chemically described as 4,4′-(1H-1,2,4Triazol-1-ylmethylene)dibenzonitrile and has the molecular weight of 285.31 g/mol. The inactive ingredients of Femara tablets are colloidal silicon dioxide, ferric oxide, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, maize starch, microcrystalline cellulose, polyethylene glycol, odium starch glycolate, talc, and titanium dioxide.

Letrozole and Bodybuilding

Letrozole can reduce the levels of estrogens in bodybuilders and others by as much as 98 percent, which is more than what Proviron and Nolvadex can offer. Furthermore, it facilitates improvements in the levels of luteinizing hormone, sex hormone-binding globulin, and follicle-stimulating hormone to a great extent. This means that bodybuilders on anabolic steroids do not need to worry about water retention, acne, or gynecomastia. In short, this miracle drug is best for both bulking and cutting cycles that involve harsh androgens.
Recommended dose of Letrozole

The recommended dose of Letrozole is 2.5 mg per day, with or without meals.

It is important to note that Letrozole tablets are required to be kept at a controlled temperature of 25°C (77°F) with excursions permitted up to 15-30°C (59-86°F).

Jan 24, 2014

Anabolic Steroids in the Treatment of Osteoporosis

Osteoporosis is a skeletal disease in which the bone mass is low and the bone tissue is degenerating.  Over time, the bone becomes more and more fragile and gains an increased tendency to fracture.  It is one of the most common bone diseases in the US, with more than 25 million people affected.

Every year, osteoporosis is responsible for causing 1.3 million fractures in various parts of the patients’ body like spine, hip, and wrist.  The most serious of these is hip fracture.  About 5 to 20% of osteoporosis patients with hip fracture die within a year, and 50% others become incapacitated.

The term osteoporosis means “porous bones.”  The skeleton is made up of a thick outer covering and a strong inner lattice comprised mainly of collagen, calcium, and other minerals.  This inner lattice looks somewhat like a honeycomb.  The spaces between them are filled with blood vessels and bone marrow.

When these spaces become bigger, osteoporosis occurs.  Bigger spaces between the bones cause the bones to be fragile and to break easily.  Osteoporosis is a condition affecting the whole skeleton, although the most common effects are fractures in the hip, spine, and hip.

The elderly face greater risk of developing osteoporosis, and consequently, the chances of having the disease increase with age.  Osteoporosis in patients also tends to worsen with age.  The incidence of fractures due to osteoporosis is expected to increase in the next 60 years.

This disease is caused by a number of factors, the first one being hormone deficiency.  Women in particular are more prone to osteoporosis than men because bone loss in women becomes accelerated 5 years after menopause.  Other factors that are known to cause or increase the chances of developing this skeletal disease include low calcium intake, having a sedentary lifestyle, drinking too much alcohol, and smoking.

One of the treatments being done for osteoporosis is the use of anabolic steroids.   These have been found to help patients, specially the very elderly ones, who are experiencing bone loss at a rapid rate.

Anabolic steroids are more popularly known as the substances that are used to enhance body building and muscle gain.  These substances are also being used widely in medicine, and treatment for osteoporosis is one of its important applications.  Anabolic steroids have been shown to stimulate the formation of new bone, to increase the absorption of calcium, and to provide relief from spinal fracture pain.

According to studies, administration of anabolic steroids to osteoporosis patients resulted in an increase in bone mass in both men and women.  Another advantage of using steroids is that the patients’ fat tissue gets converted into muscles, which helps to strengthen the body.

About 3% of bone mass is gained every year as a result of anabolic steroid administration, with the maximum effect being observed during the first months of treatment.  This gain in bone mass is attributed to the anabolic steroid’s ability to stimulate bone formation and to promote muscle tissue growth over fat tissue growth.  Anabolic steroids have also been shown to increase the absorption of calcium in the body by activating vitamin D.

Jan 17, 2014

Low Diversity of Bacteria May Increase Risk for Asthma

Low gut microbial diversity in the intestines of infants can increase the risk for asthma development. These are the findings of the age 7 follow-up in a multi-year study led by researchers at Linköping University in Sweden.

 In 2011 the results of a comprehensive survey of the intestinal microbiota of allergic and healthy children were published. In the samples from the infancy period, the degree of variation and diversity of the bacteria strains was significantly lower among those who had developed allergic eczema when they were two years old.

A follow-up study was conducted when the 47 participating infants reached their seventh birthday. By then eight of them - 17% - were suffering from chronic asthma. 28% had hay fever, 26% still had eczema, and 34% reacted to the allergens in a skin prick test. But it was only the asthma cases that could be connected to low intestinal microbial diversity at the age of one week and one month.

It might seem a bit of a stretch to think the contents of the intestines could influence what happens in the airways. The results of this study, however, give further credence to this connection, which has previously been demonstrated in animal studies "A high diversity of gut microbiota during the first months of life seems to be important for the maturation of the immune system," says Thomas Abrahamsson, paediatrician and researcher at Linköping University, and principal author of the article.

The hypothesis is that in order to function effectively, the immune system needs to be "trained" by large numbers of different microorganisms. In the absence of sufficient stimulation from large numbers of different bacteria, the system may overreact to innocuous antigens it encounters.

A high gut microbial diversity has also been shown to strengthen the barrier function of the mucous membrane. "We are speculating that a deficient maturity of the immune system at an earlier age and a less efficient mucosa barrier function can open the way to certain types of viral infection that can be linked to the development of asthma," says senior author Maria Jenmalm, professor of experimental allergology.

The analysis of the bacteria flora in the children's stools was carried out using a method known as 454 pyro sequencing at the Science for Life Laboratory, in conjunction with researchers Anders Andersson and Lars Engstrand. This is a powerful genetic method that identifies DNA sequences typical of different bacterial species, including those that cannot be cultivated in the traditional way.

Jan 8, 2014

Gluten allergy doesn't really exist

A leading allergy doctor has debunked a host of myths, saying that gluten allergy doesn't exist - and nor do hypoallergenic pets.

Dr David Stukus, an allergy specialist from Columbus, Ohio, wrote a presentation debunking various common allergy misconceptions after years of hearing patients declare inaccuracies. One pet peeve is the patients who say they can't eat bread because they're allergic to gluten, he says. "There's this claim about 'gluten allergy,' which really doesn't exist,"

"It's not really a recognised allergy. Wheat is a recognised allergy - but a lot of people will misinterpret that as gluten. Wheat allergy does not necessarily equal an allergy to all gluten. He continued: "Gluten has been blamed for all that ails humanity."

In fact, there are only three disorders that can be scientifically attributed to gluten, he says: coeliac disease, wheat allergies and non-coeliac gluten sensitivity. Coeliac disease is what's known as an autoimmune condition. This is where the immune system mistakenly attacks healthy tissue.

Patients with non-coeliac gluten sensitivity (NCGS) display gluten sensitivity symptoms - such as bloating, diarrhoea and stomach pain - but test negative for the disease despite symptoms disappearing on a gluten-free diet. "If you think you may have an allergy, you should see a certified allergist for proper evaluation, testing, diagnosis and treatment," Dr Stukus said. Also in the firing line are so-called hypoallergenic dogs.

Dr Stukus said: "Unfortunately, there is no such thing as a truly hypoallergenic dog or cat. "Allergens are released in saliva, sebaceous glands and perianal glands. It's not the fur people are allergic to. "It is true that some breeds are more bothersome for allergy sufferers than others" - which is why some people are fine around some breeds and not others.

"Many early medical beliefs have been proven to be incorrect as research has advanced. Unfortunately, some of these beliefs are still on the Internet, where an astonishing 72%  of users turn to for health information."

Another widely circulated myth is that people suffering from an egg allergy can't have such jabs - as they may include tiny bits of egg protein.

He explained: "Egg embryos are used to grow viruses for vaccines such as the flu, yellow fever and rabies shots. "However, it's now safe to get the flu shot, which can help prevent serious illness, but a referral to an allergist is recommended beforehand is recommended."

He also advises against home allergy tests, which can be unreliable. 'These tests might be able to reveal sensitisation, but being sensitized to a certain allergen, like milk, doesn't mean you're allergic. "These sort of at-home screening tests are not reliable and can often lead to misinterpretation, diagnostic confusion and unnecessary dietary elimination."