Allergy - heightened sensitivity to the effects of some body of environmental factors, known as allergens.
The cause of allergies is the impact on the body of allergy. This may be not only drugs but also food, household dust, animal hair, pollen plants, household chemicals, cosmetics, cold, sunshine and much more. Will there be a man or not allergy, rooted in heredity. If one parent suffers from allergies, the probability of its occurrence in the child - 30%. Contribute to the development of allergies psychic and emotional overload, hypodynamia, poor nutrition.
A special group of physical factors such as heat, cold, as a result of which the body without the involvement of immune mechanisms can develop pseudo allergic reaction (pseudo allergy).
The largest spread classification proposed Djelom and Kumbsom:
1. Anaphylactic type. These include: anaphylactic shock, hives, pollinosis, a topic bronchial asthma, Bannister's disease, allergic rhinitis, a topic dermatitis (neurodermatitis).
2. Cytotoxic type: immune leukopenia, immune thrombocytopenia, hemolytic anemia and others.
3. Type Artyusa - damaged immune complex: exogenous allergic alveolitis; serum disease, rheumatoid arthritis, systemic lupus erythematosus; others.
4. Delayed hypersensitivity is the basis of the following allergic reactions: contact dermatitis, infectious-allergic bronchial asthma; infectious-allergic rhinitis; others.
The first three relate to the type of immediate allergic reactions, their effect after repeated exposure to allergen moving in the interval of 15-20 minutes to several hours. The fourth type of allergy - delayed-type hypersensitivity - develops after 1-2 days.
The flow. In response to the introduction of the body arise allergen-specific allergic reactions in the process during which distinguish 3 stages:
1. immunological stage - takes place the development of antibodies to the allergen, or lymphocytes are able to interact with them;
2. pathochemical - when re-enters the body of the allergen occurs a number of biochemical reactions to the allocation of histamine and other substances that cause damage to cells of tissues, organs;
3. pathophysiologic stage - actually clinical picture of allergic reaction.
Clinical and experimental observations have shown that over and the development of allergic reaction depends on the higher divisions of the nervous system (for example, increased flow of allergic diseases under the influence of negative emotions, the development of severe allergic reactions to a number of food allergens after craniocerebral injury, etc.) and Also on hormone of the body (such as improving the flow of certain allergic diseases during pregnancy, etc.).
In turn, patients with allergic diseases altered sensitivity to different environmental factors. For example, described increasing sensitivity in patients with infectious-allergic asthma, rheumatism, tuberculosis, brucellosis to adverse weather conditions. This is worsening the main disease, the volatility of heat, rocket-propelled vessels and other signs of autonomic dysfunction and central nervous system.
Allergies can manifest itself in different ways:
But at the root of all kinds of allergies is the single immunologic mechanism. When predisposed to allergies people faced with "his" allergens, then his body starts out in immunoglobulin E. The complex allergen-immunoglobulin E causes the release of histamine, which is the main mediator of allergic inflammation. Hence the long-running nose, itching in the nose, the urge to sneezing, redness and watering eyes, skin rash and itching of skin, shortness of breath.
Treatment. Alas, freeing patients from a genetic predisposition to allergies modern medicine can not.
The most common treatment for allergies is medically - antihistaminic use of drugs.
"Patriarch" among them is Dimedrol, which, unfortunately, has side effects. Patients appear drowsiness, dizziness, sometimes even headache and dry mouth.
In the 70's have antihistamine 2 nd generation deprived of the deficiencies and operating more efficiently.